Selectivity for eIF4E

Lattice supports single bilayer he spherical membrane surrounding the poxvirus genome begins to form as an open, cup-like structure. Some have argued that the edge of the cup must be composed of two closely apposed membranes (imagine a collapsed vesicle); otherwise, the hydrophobic edges of a single membrane would be exposed to the cytoplasm. But on page 269, John Heuser confirms that poxvirus has only a single membrane bilayer. He finds that the growing membrane is stabilized by a proteinaceous lattice. Heuser imaged freeze-fractured cells infected with poxvirus. Freeze-fracturing T